Publication List

Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt
AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP. A
YY1-dependent increase in aerobic metabolism is indispensable for intestinal
organogenesis. Development. 2016 Oct 15;143(20):3711-3722. PubMed PMID: 27802136;
PubMed Central PMCID: PMC5087649.

Ma Y, Faller WJ, Sansom OJ, Brown ER, Doig TN, Melton DW, Machesky LM. Fascin
expression is increased in metastatic lesions but does not correlate with
progression nor outcome in melanoma. Melanoma Res. 2015 Apr;25(2):169-72. doi:
10.1097/CMR.0000000000000135. PubMed PMID: 25535872.

Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN,
Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov
A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K,
Adams PD. HIRA orchestrates a dynamic chromatin landscape in senescence and is
required for suppression of neoplasia. Genes Dev. 2014 Dec 15;28(24):2712-25.
doi: 10.1101/gad.247528.114. PubMed PMID: 25512559; PubMed Central PMCID:
PMC4265675.

Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C,
Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB,
Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis
AE, Sansom OJ. mTORC1-mediated translational elongation limits intestinal tumour
initiation and growth. Nature. 2015 Jan 22;517(7535):497-500. doi:
10.1038/nature13896. PubMed PMID: 25383520; PubMed Central PMCID: PMC4304784.

Muinonen-Martin AJ, Susanto O, Zhang Q, Smethurst E, Faller WJ, Veltman DM,
Kalna G, Lindsay C, Bennett DC, Sansom OJ, Herd R, Jones R, Machesky LM, Wakelam
MJ, Knecht DA, Insall RH. Melanoma cells break down LPA to establish local
gradients that drive chemotactic dispersal. PLoS Biol. 2014 Oct
14;12(10):e1001966. doi: 10.1371/journal.pbio.1001966. PubMed PMID: 25313567;
PubMed Central PMCID: PMC4196730.

Lindsay CR, Li A, Faller W, Ozanne B, Welch H, Machesky LM, Sansom OJ. A
Rac1-independent role for P-Rex1 in melanoblasts. J Invest Dermatol. 2015
Jan;135(1):314-8. doi: 10.1038/jid.2014.323. PubMed PMID: 25075639; PubMed
Central PMCID: PMC4269807.

Li A, Morton JP, Ma Y, Karim SA, Zhou Y, Faller WJ, Woodham EF, Morris HT,
Stevenson RP, Juin A, Jamieson NB, MacKay CJ, Carter CR, Leung HY, Yamashiro S,
Blyth K, Sansom OJ, Machesky LM. Fascin is regulated by slug, promotes
progression of pancreatic cancer in mice, and is associated with patient
outcomes. Gastroenterology. 2014 May;146(5):1386-96.e1-17. doi:
10.1053/j.gastro.2014.01.046. PubMed PMID: 24462734; PubMed Central PMCID:
PMC4000441.

Ma Y, Li A, Faller WJ, Libertini S, Fiorito F, Gillespie DA, Sansom OJ,
Yamashiro S, Machesky LM. Fascin 1 is transiently expressed in mouse melanoblasts
during development and promotes migration and proliferation. Development. 2013
May;140(10):2203-11. doi: 10.1242/dev.089789. PubMed PMID: 23633513; PubMed
Central PMCID: PMC3912869.

Lindsay CR, Lawn S, Campbell AD, Faller WJ, Rambow F, Mort RL, Timpson P, Li
A, Cammareri P, Ridgway RA, Morton JP, Doyle B, Hegarty S, Rafferty M, Murphy IG,
McDermott EW, Sheahan K, Pedone K, Finn AJ, Groben PA, Thomas NE, Hao H, Carson
C, Norman JC, Machesky LM, Gallagher WM, Jackson IJ, Van Kempen L, Beermann F,
Der C, Larue L, Welch HC, Ozanne BW, Sansom OJ. P-Rex1 is required for efficient
melanoblast migration and melanoma metastasis. Nat Commun. 2011 Nov 22;2:555.
doi: 10.1038/ncomms1560. PubMed PMID: 22109529; PubMed Central PMCID: PMC3400057.

Gremel G, Ryan D, Rafferty M, Lanigan F, Hegarty S, Lavelle M, Murphy I,
Unwin L, Joyce C, Faller W, McDermott EW, Sheahan K, Ponten F, Gallagher WM.
Functional and prognostic relevance of the homeobox protein MSX2 in malignant
melanoma. Br J Cancer. 2011 Aug 9;105(4):565-74. doi: 10.1038/bjc.2011.249.
PubMed PMID: 21730974; PubMed Central PMCID: PMC3170959.

Faller WJ, Rafferty M, Hegarty S, Gremel G, Ryan D, Fraga MF, Esteller M,
Dervan PA, Gallagher WM. Metallothionein 1E is methylated in malignant melanoma
and increases sensitivity to cisplatin-induced apoptosis. Melanoma Res. 2010
Oct;20(5):392-400. PubMed PMID: 20848733.

Ryan D, Rafferty M, Hegarty S, O'Leary P, Faller W, Gremel G, Bergqvist M,
Agnarsdottir M, Strömberg S, Kampf C, Pontén F, Millikan RC, Dervan PA, Gallagher
WM. Topoisomerase I amplification in melanoma is associated with more advanced
tumours and poor prognosis. Pigment Cell Melanoma Res. 2010 Aug;23(4):542-53.
doi: 10.1111/j.1755-148X.2010.00720.x. PubMed PMID: 20465595.

Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D,
Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM,
Esteller M. A microRNA DNA methylation signature for human cancer metastasis.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13556-61. doi:
10.1073/pnas.0803055105. PubMed PMID: 18768788; PubMed Central PMCID: PMC2528872.

Rafferty M, Faller WJ, Moss C, McCormack J, Mãlandsmo GM, Easty DJ, Gallagher
WM. Real-time quantitative reverse transcriptase-polymerase chain reaction
analysis of melanoma progression-associated genes. Anticancer Res. 2007
May-Jun;27(3A):1301-7. PubMed PMID: 17593623.